Translational pharmacology pursues research at the interface of non-clinical and clinical sciences. Our scientific focus is the personalization of drug therapy for chronic diseases. We investigate mechanisms of variability in therapeutic and adverse drug effects using laboratory experiments and carefully conducted proof-of-concept clinical studies.
We are particularly interested in lipid mediators in the eicosanoid biosynthetic-response pathway. Most cells in the organism have the capacity to form eicosanoids, which have important regulatory functions in many physiological and pathological processes. These include inflammation, inflammatory pain, blood pressure regulation, atherosclerosis, thrombosis, tumor growth and immunity. We conduct deep-phenotyping studies in model systems and in humans, which involve precise measurements of molecular network topologies and dynamics using the omics technologies.
Tilo Grosser, M.D.
Professor and Head of Translational Pharmacology
Systems Pharmacology
Lenny Ferrer, Ph.D.
Viktoria Fuchs, M.Sc.
Jörg Wegener, Ph.D., Senior Lecurer
Immunology
Bianca Jütte, PhD
Bioinformatics
Fabian Banze, B.Sc.
Clinical Research Coordination
Insa Wingendorf, MPH
Melanie Kriete
Open Positions:
Sekretär*in (m/w/d) AG 13 / Centrum für Translationale Medizin und Therapie